Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of SRY in human tissue homogenates, cell lysates.
Target Information: This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome)\, translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]